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AssigneeMerz + Co. GmbH & Co.
InventorsEberhard Nurnberg, Erhard Seiller, Bernd Kuhn
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The application discloses a process for the manufacture of mechanically-stable, readily-disintegratable tablets made of small preformed, preferably rounded, particles or pellets containing a high percentage of active ingredient in which--prior to compression--the particles are coated with an aqueous or aqueous/organic suspension containing water-soluble polyvinyl alcohol having an ester content of 19.4 to 6.7%, a disintegrant, and finely-divided cellulose, the remainder being excipients such as additional colloids, adjuvants, dyes, and/or flavors and the suspending liquid, and dried, the stable but readily-friable tablet product thus-produced, and a method of delivering an active ingredient by the employment of such a tablet for oral ingestion.
Process for the manufacture of mechanically-stable, readily-disintegratable tablets which are disintegratable in water within a period of 5 of 300 seconds comprising small preformed individual pellets or particles containing active ingredient wherein
A mechanically-stable, readily-disintegratable tablet comprising small preformed particles or pellets containing active ingredient surrounded by an aqueous or aqueous-organic suspension which consists essentially of
Dependencies are inferred from the claim text.