Biologically active drug polymer derivatives and method for preparing same
AssigneeDebiopharm S.A.
InventorsFrancesco Veronese, Luciana Sartore, Piero Orsolini, Romano Deghenghi
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Abstract
New biologically active drug polymer derivatives, namely peptides or protein derivatives, are useful medicaments and are represented by the generic formula: RO--(CH.sub.2 --CH.sub.2 O).sub.n --(CO)--NH--X--(CO)--NH--Z (I) wherein R represents a lower alkyl group, n is an integer comprised between 25 and 250, X when combined with adjacent NH and CO groups represents an amino acid or a dipeptide or tripeptide residue, and Z when combined with the adjacent NH group represents a biologically active peptide or protein or NH or NH.sub.2 containing drug residue.
Claims6
Biologically active drug polymer derivatives having the formula
- RO--(CH.sub.2 --CH.sub.2 O).sub.n --(CO)--NH--X--(CO)--NH--Z (I)
- wherein
- R represents a lower alkyl group,
- n is an integer between 25 and 250,
- X when combined with adjacent NH and CO groups represents an amino acid or a dipeptide or tripeptide residue, and
- Z when combined with the adjacent NH group represents a biologically active peptide or protein or NH or NH.sub.2 containing drug residue.
Dependencies are inferred from the claim text.