Polychelant compounds
AssigneeSalutar, Inc.
InventorsDavid B. Love, William C. Dow, Richard J. Himmelsbach, Alan D. Watson, Scott M. Rocklage
Life of this patent
Estimating the term…
Abstract
There are disclosed polychelant compounds, that is multi-site metal chelating agents, and chelates formed therewith. The polychelants and especially their paramagnetic metal, heavy metal or radioactive metal polychelates are particularly suitable for use in diagnostic imaging, heavy metal detoxification or radiotherapy. The polychelants have a linear or branched oligomeric structure comprising alternating chelant and linker moieties bound together by amide or ester moieties the carbonyl groups whereof being adjacent the chelant moieties, each polychelant comprising at least two said chelant moieties capable of complexing a metal ion.
Claims25
A branched oligomeric polychelant comprising alternating cyclic polyazaalkane chelant and linker moieties bound together by amide moieties the carbonyl groups whereof being adjacent the chelant moieties, wherein said polychelant comprises at least three said chelant moieties capable of complexing a metal ion, and wherein the sum of said chelant and linker moieties is no more than 100, or a salt or chelate of said polychelant.
Dependencies are inferred from the claim text.