Gel-in-matrix containing a fractured hydrogel
AssigneeFMC Corporation
InventorsRichard B. Provonchee, Francis H. Kirkpatrick
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Abstract
A three dimensional porous matrix, such as a reticulated open-cell foam, having within its matrix structure a mechanically-fractured hydrogel containing a network of fracture channels. The mechanically-fractured hydrogel may be a gel that has been partially dewatered by compression of the gel in situ. The porosity of the gel-in-matrix makes it useful for chromatographic applications and for immobilization of biologically-active components, where efficient, intimate contact of the hydrogel with a liquid medium is important.
Claims50
A gel-in-matrix combination comprising a three-dimensional porous support matrix and a porous fractured hydrogel fixedly disposed therein, in which said fractured hydrogel has:
- (a) a void volume of about 10-90%;
- and (b) a plurality of porous fractures comprising channels having a mean characteristic dimension of about 0.1-1,000 .mu.m.
Dependencies are inferred from the claim text.