Polycyclic amines useful as cerebrovascular agents

A compound of formula ##STR176## or a pharmaceutically acceptable salt thereof wherein:

• R.sup.1 and R.sup.2 are each independently
• hydrogen,
• loweralkyl,
• loweralkenyl,
• arylloweralkyl, or
• a pharmaceutically acceptable labile group;
• R.sup.3 and R.sup.4 are each independently
• hydrogen,
• loweralkyl,
• hydroxy,
• loweralkoxy,
• loweralkylthio,
• halogen,
• trifluoromethyl,
• amino,
• monoloweralkylamino,
• diloweralkylamino;
• aminomethyl,
• hydroxymethyl,
• methoxymethyl,
• 1-hydroxyethyl,
• 1-methoxyethyl,
• hydroxyphenylmethyl,
• methoxyphenylmethyl,
• 1-aminoethyl,
• aminophenylmethyl,
• 1-loweralkylaminoethyl, or
• lowerakylaminophenylmethyl,
• R.sup.5 and R.sup.6 are each independently
• hydrogen,
• loweralkyl,
• loweralkenyl,
• hydroxy,
• loweralkoxy,
• loweralkylthio,
• aldehyde,
• loweralkylcarbonyl,
• hydroxymethyl,
• loweralkoxymethyl,
• 1- or 2-hydroxyethyl,
• 1- or 2-loweralkoxyethyl,
• amino,
• diloweralkylamino,
• aminomethyl,
• loweralkylaminomethyl,
• diloweralkylaminomethyl,
• 1- or 2-aminoethyl,
• 1- or 2-loweralkylaminoethyl,
• 1- or 2-diloweralkylaminoethyl;
• the in ring C is an optional double bond,
• X' is
• --CH.sub.2 --,
• --CH--, and
• n is 1,
• X is
• --CHR.sup.7 S--,
• --SCHR.sup.7 --, or
• wherein R.sup.7 is
• hydrogen,
• loweralkyl,
• hydroxy,
• methoxy,
• methoxyloweralkyl,
• hydroxyloweralkyl,
• aminoloweralkyl,
• mono- and diloweralkylaminoloweralkyl,
• fluoro-substituted loweralkyl.