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US 5,274,002 AGranted
Trisubstituted phenyl analogs having activity for congestive heart failure
AssigneeWarner-Lambert Company
InventorLynn D. Hawkins
Life of this patent
Estimating the term…
Abstract
Novel trisubstituted phenyl analogs are now found to have activity as for the treatment of congestive heart failure.
Claims40
A compound of the formula (I) ##STR7## wherein R.sup.1 is cycloalkyl of three to six carbons;
- Q is XR.sup.2 wherein R.sup.2 is lower alkyl and X is O or S;
- NR.sup.3 R.sup.4 wherein R.sup.3 and R.sup.4 are independently hydrogen or lower alkyl;
- or NO.sub.2 ;
- A is a bond, straight or branched alkylenyl of from one to seven carbons or alkenylenyl of from two to six carbons having one, two, or three double bonds having the alkylenyl or the alkenylenyl optionally interrupted by O, S, or NR.sup.5 ;
- Y is CO.sub.2 R.sup.5 wherein R.sup.5 is hydrogen, methyl or ethyl;
- CHO;
- CH.sub.2 OH;
- NO.sub.2 ;
- or NR.sup.3 R.sup.4 wherein R.sup.3 and R.sup.4 are independently as defined above;
- and the pharmaceutically acceptable salts thereof.
7 more elements
3-(3-Cyclopentoxy-4-methoxyphenyl)-1-propyl bromide.
1-n-Butyl-3-cyclopentoxy-4-methoxybenzene.
1-Amino-3-(3-cyclopentoxy-4-methoxyphenyl)-n-propane.
Methyl N-(3-cyclopentoxy-4-methoxybenzyl)glycine ester hydrochloride.
Dependencies are inferred from the claim text.