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US 5,273,745 AGranted
Virus-modified tumor vaccines for immunotherapy of tumor metastases
AssigneeVolker R. Schirrmacher
InventorVolker Schirrmacher
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Abstract
The invention discloses a virus-modified tumour-specific vaccine consisting of corresponding separated tumour cells inactivated by irradiation and incubated with NDV (Newcastle Disease Virus) under sterile conditions in serum-free medium. The vaccine may optionally be irradiated again prior to application.
Claims20
A tumor-specific immunotherapeutic agent comprising separated tumour cells isolated from human tumours, inactivated by radiation and incubated with NDV-virus under sterile conditions in serum-free medium to produce virus-modified tumour cells.
Dependencies are inferred from the claim text.