Nisin compositions for use as enhanced broad range bactericides
AssigneeApplied Microbiology, Inc.
InventorsPeter Blackburn, June Polak, Sara-Ann Gusik, Stephen D. Rubino
Life of this patent
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Abstract
Bacteriocin compositions comprising lanthionine containing bacteriocins and non-bactericidal agents. When the bacteriocin compositions are combined with a suitable carrier with each component present in sufficient quantities such that the composition is effective against Gram negative bacteria in addition to Gram positive bacteria, they become enhanced, rapid acting, broad range bactericides suitable for a variety of applications.
Claims10
A lanthionine-containing-bacteriocin bactericidal composition comprising a lanthionine-containing bacteriocin in combination with a chelating agent wherein the bacteriocin and the chelating agent are present in quantities such that the composition is effective against gram negative bacteria as measured by effectiveness against Salmonella typhimurium, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacteroides gingivalis and Actinobacillus actinomycetescomitans and has enhanced effectiveness against gram positive bacteria as measured by enhanced effectiveness against Staphylococcus aureus, Streptococcus mutans, Listeria monocytogenes, Streptococcus agalactiae and Coryneform bacteria.
A lanthionine-containing-bacteriocin bactericidal composition comprising a lanthionine-containing bacteriocin, in combination with a chelating agent and a surfactant selected from the group consisting of glycerides, fatty acids, emulsifiers, quaternary compounds, amphoteric surfactants and nonionic surfactants wherein the bacteriocin, the chelating agent and the surfactant are present in quantities such that the composition is effective against gram negative bacteria as measured by effectiveness against Salmonella typhimurium, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacteroides gingivalis and Actinobacillus actinomycetescomitans and has enhanced effectiveness against gram positive bacteria as measured by enhanced effectiveness against Staphylococcus aureus, Streptococcus mutans, Listeria monocytogenes, Streptococcus agalactiae and Coryneform bacteria.
A nisin-containing bactericidal composition comprising nisin in combination with a chelating agent in a suitable carrier wherein the nisin and the chelating agent are present in quantities such that the composition is effective against gram negative bacteria as measured by effectiveness against Salmonella typhimurium, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacteroides gingivalis and Actinobacillus actinomycetescomitans and has enhanced effectiveness against gram positive bacteria as measured by enhanced effectiveness against Staphylococcus aureus, Streptococcus mutans, Listeria monocytogenes, Streptococcus agalactiae and Coryneform bacteria.
Dependencies are inferred from the claim text.