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US 5,260,059 AGranted
Treatment of open-angle glaucoma by modulation matrix metalloproteinases and their inhibitor
AssigneeThe State of Oregon Acting by and through the State Board of Higher Education on Behalf of Oregon Health Sciences University
InventorsTed S. Acott, J. Preston Alexander, John M. B. Bradley
Life of this patent
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Abstract
The abstract isn’t available for this document.
Claims5
A method for treating open-angle glaucoma in an eye of a subject having glaucoma, comprising:
- providing to the subject's trabecular meshwork or tissue in direct fluid communication therewith, by site specific delivery means, an extracellular matrix metalloproteinase/tissue inhibitor (MMP/TIMP) ratio modulating substance in an effective amount to increase an MMP/TIMP ratio and reduce intraocular pressure, wherein the modulating substance is selected from the group consisting of MMP-1, MMP-2, or MMP-3.
Dependencies are inferred from the claim text.