Controlled release osmotic infusion system
AssigneePharmetrix Corporation
InventorsAmulya L. Athayde, Rolf A. Faste
Life of this patent
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Abstract
A portable osmotic infusion device assembly, having two pouches in pressure transmitting relationship, the first containing infusate and the second, a driving fluid. The driving fluid is created and pressurized by activation of an osmotic pump, and the rate of infusion is controlled by a rate-controlling means. The infusate pouch is manufactured separately and can be stored apart from the rest of the system.
Claims24
A portable infusion device assembly comprising:
- a. a first pouch containing infusate and fitted with a dispensing nozzle;
- b. a second pouch in pressure-transmitting relationship to the aforesaid first pouch;
- c. an integral power source comprising:
- a pressure-generating means for generating pressure in aforesaid second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when permeant contacts osmagent;
- an activating means for initiating the action of the aforesaid power generating means;
- a rate-controlling means for regulating the volume change of the aforesaid first pouch, comprising a semipermeable membrane;
- d. a fluid-transport means in liquid transmitting relationship between the aforesaid power chamber and the aforesaid delivery chamber, and,
- e. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment;
- and,
- f. a housing containing the aforesaid first and second pouches and in restraining relationship to the aforesaid first and second pouch.
A portable infusion device assembly comprising:
- a. a first pouch containing infusate and fitted with a dispensing nozzle;
- b. a second pouch in pressure-transmitting relationship to the aforesaid first pouch;
- c. an integral power source comprising:
- a pressure-generating means for generating pressure in aforesaid second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when permeant contacts osmagent;
- an activating means for initiating the action of the aforesaid power generating means;
- a rate controlling means for regulating the volume change of the aforesaid first pouch, comprising a semipermeable membrane;
- d. a fluid-transport means in liquid transmitting relationship between the aforesaid power chamber and the aforesaid delivery chamber, and,
- e. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment;
- and,
- f. a housing containing the aforesaid first pouch, second pouch, and power source, and in restraining relationship with the aforesaid first and second pouches.
A method for infusing a patient, comprising connection of said patient to a portable infusion device, said device comprising:
- a. a first pouch containing infusate and a dispensing nozzle;
- b. a second pouch in pressure-transmitting relationship to the aforesaid first pouch;
- c. an integral power source comprising:
- a pressure-generating means for generating pressure in aforesaid second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when permeant contacts osmagent;
- an activating means for initiating the action of the aforesaid power generating means;
- a rate-controlling means for regulating the volume change of the aforesaid first pouch, comprising a semipermeable membrane;
- d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment;
- e. a housing containing the aforesaid first and second pouches and in restraining relationship to the aforesaid first and second pouches;
- and,
- f. activating said device.
A method for infusing a patient, comprising connection of said patient to a portable infusion device, said device comprising:
- a. a first pouch containing infusate and a dispensing nozzle;
- b. a second pouch in pressure-transmitting relationship to the aforesaid first pouch;
- c. an integral power source comprising:
- a pressure-generating means for generating pressure in aforesaid second pouch, comprised of an osmagent and a liquid permeant;
- wherein a driving fluid is produced when permeant contacts osmagent;
- an activating means for initiating the action of the aforesaid power generating means;
- a rate controlling means for regulating the volume change of the aforesaid first pouch, comprising a semipermeable membrane;
- d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment;
- e. a housing containing the aforesaid first pouch, second pouch, and power source, and in restraining relationship with the aforesaid first and second pouches;
- and,
- f. activating said device.
Dependencies are inferred from the claim text.