Retroviral protease inhibiting compounds

A compound of the formula:

• ##STR7## wherein R.sub.1 is loweralkyl, cycloalkyl, phenyl, substituted loweralkyl, substituted cycloalkyl or substituted phenyl wherein the loweralkyl, cycloalkyl or phenyl group is substituted with one or two substituents independently selected from group is substituted with one or two substituents independently selected from hydroxy, alkoxy, thioalkoxy and halo;
• R.sub.2 is phenyl or substituted phenyl wherein the phenyl ring is substituted with one or two substituents independently selected from hydroxy, alkoxy, thioalkoxy and halo;
• R.sub.3 is ##STR8## wherein m is 1 and R.sub.4 is hydrogen, loweralkyl, cycloalkylalkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, thioalkoxyalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, carboxyalkyl, alkoxycarbonylalkyl or aminocarbonylalkyl and
• T is ##STR9## wherein R.sub.6 is pyridyl or substituted pyridyl wherein the pyridyl ring is substituted with one or two substituents independently selected from hydroxy, alkoxy, amino, alkylamino, dialkylamino, polalkoxy, haloalkyl, cycloalkyl, aryl, arylalkyl, --COOH, --SO.sub.3 H, loweralkyl and halo, V is O or S, W is CH.sub.2, --CH.sub.2 CH.sub.2 --, --CH.dbd.CH-- or --D--CH.dbd.CH-- wherein D is O, S or NH and Y is absent, O, S or N(R.sub.7) wherein R.sub.7 is hydrogen or loweralkyl;
• and Z is --C(O)-- or --CH(OH)--;
• or a pharmaceutically acceptable salt thereof;
• wherein the term aryl as used herein refers to phenyl, naphthyl, tetrahydronaphthyl or indanyl.