Compositions comprising ecteinascidins and a method of treating herpes simplex virus infections therewith
AssigneeThe Board of Trustees of the University of Illinois
InventorsKenneth Rinehart, Sakai Ryuichi, Tom G. Holt
Life of this patent
Estimating the term…
Abstract
The present invention relates to pharmaceutical compositions comprising matter extracted from the well-known and readily available tropical marine invertebrate, Ecteinascidia turbinata, and designated herein as ecteinascidins, and to the use of such compositions as antibacterial, anti-viral, and/or antitumor agents in mammals.
Claims10
A pharmaceutical composition comprising one or more ecteinascidin species selected from the group consisting of Et 736, Et 722, Et 743, Et 729, Et 745, Et 759(a), Et 770 and Et 729, in combination with a pharmaceutically acceptable carrier, diluent or excipient.
A method of treating herpes simplex virus (Type I) infections in mammals comprising administering to a mammal in need of such treatment, an anti-HSV-I effective dosage of a pharmaceutical composition comprising an ecteinascidin (Et) selected from the group consisting of Et 736, Et 722, Et 743, Et 729, Et 745, Et 759(a), Et 770, Et 729, or mixtures thereof, in a suitable carrier or diluent.
Dependencies are inferred from the claim text.