Compositions comprising 1-substituted azacycloalkanes
AssigneeWhitby Research, Inc.
InventorsGevork Minaskanian, James V. Peck, Eric L. Nelson
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Abstract
This invention provides compositions comprising a physiologically-active agent and a compound having the structural formula ##STR1## wherein X may represent sulfur or two hydrogen atoms; R' is H or a lower alkyl group having 1-4 carbon atoms; m is 2-6; n is 0-18 and R is --CH.sub.3, ##STR2## wherein R" is H or halogen, in an amount effective to enhance the penetration of the physiologically-active agent through the skin or other membrane of the body of an animal.
Claims4
A method for topically administering an antibacterial agent to a human or animal in need thereof which comprises contacting said antibacterial agent with the skin or other membrane of the human or animal in the presence of a non-toxic, effective penetrating amount of a compound having the structural formula ##STR5## wherein X is two hydrogen;
- atoms;
- m is 4;
- n is 4-17;
- R is --CH.sub.3, and R' is H.
A method for administering an effective amount of an antibacterial agent through the skin or other membrane of a human or animal in need thereof which comprises contacting said antibacterial agent with said skin or other membrane in the presence of a non-toxic compound having the structural formula ##STR6## wherein X is two hydrogen atoms;
- R' is H or a lower alkyl group having 1-4 carbon atoms;
- m is 2-6;
- n is 0-18 and R is --CH.sub.3, ##STR7## R" is H or halogen.
Dependencies are inferred from the claim text.