Anti-thrombogenic blood treating system
AssigneeToray Industries, Inc.
InventorsRyozo Terada, Kazumi Tanaka, Tetsunosuke Kunitomo
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Abstract
An anti-thrombogenic blood treating system, comprising selectively permeable hollow yarn membranes made of a composition containing a copolymer with polyethylene oxide component, and headers, catheters and circuits respectively covered on the blood contact surface with a heparinized hydrophilic copolymer containing vinyl chloride as a component monomer or a hydrophilic copolymer with polyethylene oxide component, in combination. All the blood contact surfaces are made anti-thrombogenic to allow, for the first time, the long-time extracorporeal circulation without intracorporeal administration of heparin.
Claims3
An anti-thrombogenic blood treating system, comprising selectively permeable hollow yarn membranes made of a composition containing a copolymer consisting of a monomer with a polyethylene oxide component of 5 or more in polymerization degree and a polymerizable carbon-carbon double bond in the same molecule and a monomer with a polymerizable carbon-carbon double bond, and headers, catheters and circuits respectively covered on the blood contact surface with a heparinized hydrophilic copolymer containing vinyl chloride as a component monomer, in combination.
An anti-thrombogenic header comprising a layer of a heparinized hydrophilic copolymer containing vinyl chloride as a component monomer, said layer being formed on the inside, blood-contacting surface of said header, and wherein said header has a blood inlet port on an inlet side, and has an inner diameter, and has an inside space adjacent said blood inlet port, and has a bundle of hollow yarn membranes having an outer diameter connected to said inside space, and wherein said blood inlet port is arranged to open in a direction substantially tangential to the inside space of the header;
- wherein said inside space of said header has a height at the inlet side of about 1 to about 5 times the inner diameter of the opened blood inlet port;
- the inner diameter of the inside space is larger than the outer diameter of the hollow yarn membrane bundle by about 0 to about 2 mm;
- said blood inlet port is positioned in contact with the top of said inside space of said header;
- and said inside space has a substantially conical protrusion at its center extending toward opened end faces of the hollow yarn membranes.
Dependencies are inferred from the claim text.