Nonirritating nonionic surfactant compositions
AssigneeAllergan, Inc.
InventorsShulin Ding, Thao T. Tran
Life of this patent
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Abstract
A nonirritating, nonionic detergent surfactant composition suitable for application to and cleaning of sensitive tissue, including periocular and ocular tissue, having a low cytotoxicity and high cleaning ability includes a principal nonionic surfactant and at least one auxiliary nonionic surfactant present in the surfactant composition in sufficient amounts to increase the cleaning ability of the principal non-ionic surfactant.
Claims8
A nonirritating detergent surfactant composition suitable for application to and cleaning of sensitive tissue, said nonirritating detergent surfactant composition comprising:
- a principal nonionic surfactant comprising, Pluronic.RTM. P85, and present in said nonirritating detergent surfactant composition in a sufficient amount to clean said sensitive tissue;
- and
- two auxiliary nonionic surfactant present in said nonirritating detergent surfactant composition in sufficient amounts to increase the cleaning ability of the principal nonionic surfactant, a first auxiliary nonionic surfactant being Pluronic.RTM. F87, and a second auxiliary nonionic surfactant being octoxynol 40.
A nonirritating detergent surfactant composition having low cylotoxicity for ocular and periocular tissue, said nonirritating detergent surfactant composition comprising:
- a principal nonionic surfactant comprising Pluronic.RTM. P85, and present in said nonirritating detergent surfactant composition in a sufficient amount to clean ocular and periocular tissue;
- and
- two auxiliary nonionic surfactant present in said nonirritating detergent surfactant composition in sufficient amounts to increase the cleaning ability of the principal nonionic surfactant, a first auxiliary nonionic surfactant being Pluronic.RTM. F87, and a second auxiliary nonionic surfactant being octoxynol 40.
A method of cleaning ocular and periocular tissue comprising the steps of instilling in an eye a composition comprising a principal nonionic surfactant present in said composition in a sufficient amount to clean ocular and periocular tissue, said principal surfactant comprising Pluronic.RTM. P85, and two auxiliary nonionic surfactant present in said composition in sufficient amounts to increase the cleaning ability of the principal nonionic surfactant, a first auxiliary nonionic surfactant comprising Pluronic.RTM. F87 and a second auxiliary nonionic surfactant comprising octoxynol 40.
Dependencies are inferred from the claim text.