Contrast media comprising a paramagnetic agent and an iodinated agent for X-ray and MRI
AssigneeNycomed Imaging AS
InventorJo Klaveness
Life of this patent
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Abstract
There is provided a contrast medium comprising a physiologically tolerable paramagnetic metal species containing substance together with a water soluble iodinated X-ray contrast agent. The contrast medium can be used for both X-ray and magnetic resonance imaging of the gastro-intestinal tract but overcomes or greatly reduces the side effects experienced by mannitol-containing prior art contrast media.
Claims20
An enteral contrast medium for X-ray and MRI diagnostic imaging of a human or animal externally voided body cavity comprising a diagnostically effective amount of a physiologically tolerable paramagnetic metal species containing substance together with a sufficient amount of a water soluble iodinated X-ray contrast agent to enhance MRI imaging of said externally voided body cavity;
- wherein said paramagnetic metal species containing substance and said iodinated X-ray contrast agent are not the same molecule.
A diagnostic contrast agent kit for X-ray and MRI imaging of a human or animal externally voided body cavity comprising a diagnostically effective amount of a physiologically tolerable paramagnetic metal species containing substance, and packaged separately thereto, a sufficient amount of a water soluable iodinated X-ray contrast agent to enhance MRI imaging of said externally voided body cavity;
- wherein said paramagnetic metal species containing substance and said iodinated X-ray contrast agent are not the same molecule.
Dependencies are inferred from the claim text.