Human manganese superoxide dismutase (hMn-SOD)
AssigneeBoehringer Ingelheim International GmbH
InventorsKonrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann
Life of this patent
Estimating the term…
Abstract
The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
Claims26
A cloned gene encoding human manganese superoxide dismutase (hMn-SOD) consisting essentially of the sequence ##STR17## wherein AAG at codon 30 can be replaced by CAG and CAC at codon 32 can be replaced by CAT.
The plasmid pWS490A, pWS491A, pWS550A, pWS371A, pWS372A, pWS373A, pEO24-AB, pEO25-AC, or pEO26-AD.
Dependencies are inferred from the claim text.