US 5,240,322 A · Pharmaceutical mixing container with rotatable vaned internal magnetic mixing element

Abstract

A pharmaceutical mixing container for storing a liquid having at least two factions which tend to separate during storage. A housing has an inner volume and is closed at one end by a septum arrangement and at another end by a slidable sealing member. A vaned mixing member having a magnetic element is loosely rotatably mounted within the housing in a first recess formed in the inner volume facing portion of the sealing member and contacts the liquid faction of the pharmaceutical contained within the housing. An external magnet produces a magnetic field which extends within the inner volume and interacts with the mixing element. By rotating the magnet about the axis of the housing, the mixing member is rotated by the magnetic coupling causing turbulent waves within the liquid which provide thorough admixing for the pharmaceutical constituents. The external magnet is carried by a drive stem which engages with the sealing member and can be used to expel the mixed pharmaceutical after the septum is pierced. By controlling the speed of rotation of the magnet, thorough admixing is provided without causing mechanical damage to delicate constituents, such as crystalline factions found in NPH type insulin.

Claims16

Dependent claims

A pharmaceutical mixing container for storing liquid with a miscible component, said container comprising:

a housing having a first end, a second end and a wall structure defining an inner volume;
a closure member at said first end providing a fluid seal;
means for providing a second fluid seal so that said inner volume is closed, said means being located within said housing and having an internal recess accessible from the outside of said housing;
a mixing member mounted within said inner volume and rotatably coupled to said second fluid seal said mixing member having at least one mixing vane and being controllable by a magnetic field;
and
magnetic field generating means adapted to be positioned within said internal recess and adjacent said mixing member wherein rotation of said magnetic field generating means when positioned within magnetic coupling range of said mixing member causes said mixing member to be rotated within said housing to admix any liquid and miscible component contained therein.

3 more elements

Dependencies are inferred from the claim text.

Pharmaceutical mixing container with rotatable vaned internal magnetic mixing element

Life of this patent

Pharmaceutical mixing container with rotatable vaned internal magnetic mixing element

Life of this patent

Abstract

Claims16