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US 5,236,563 AGranted
Surface-modified bioabsorbables
AssigneeAdvanced Surface Technology, Inc.
InventorInh-Houng Loh
Life of this patent
Estimating the term…
Abstract
A bioabsorbable synthetic polymer is exposed to a gas plasma in a chamber at a pressure substantially below atmospheric for a sufficient time to increase the hydrophobicity and/or cross-linking density of a surface layer thereof and thereby modify the rate at which the polymer will hydrolyze. An accordingly modified polymer is useful for surgical implants and wound closures.
Claims16
A method of treating a bioabsorbable synthetic polymer to modify the degradation rate thereof, said method comprising the step of:
- modifying the hydrolyzation rate of said polymer by exposing said polymer to a gas plasma in a chamber at a pressure substantially below atmospheric for a sufficient time to increase the hydrophobicity or the cross-linking density or both the hydrophobicity and the cross-linking density of a surface layer thereof.
An improved bioabsorbable synthetic polymer comprising:
- a biosynthetic absorbable polymer the hydrolyzation rate of which has been modified by exposure of said polymer to a gas plasma in a chamber at a pressure substantially below atmospheric for a sufficient time to increase the hydrophobicity or the cross-linking density or both the hydrophobicity and cross-linking density of a surface layer thereof.
Dependencies are inferred from the claim text.