Process for producing inorganic biomaterial
AssigneeHoya Corporation
InventorsToshihiro Kasuga, Kiichi Nakajima
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Abstract
The present invention relates to a process for producing an inorganic biomaterial, according to which, there can be obtained an inorganic biomaterial excellent in strength and biocompatibility, having a structure in which portions constituted by crystallized glass or crystals of calcium phosphate excellent in bioactivity are dispersed in a skeleton or matrix constituted by crystals of partially stabilized zirconia and/or alumina showing high strength. Accordingly, the inorganic biomaterial is very useful as biomaterial for artificial bones, dental implants, etc.
Claims9
A process for producing an inorganic biomaterial, which comprises:
- a first step of melting a mixture of glass raw materials and cooling it to thereby prepare glass containing the following components of the following proportions
- ______________________________________ CaO 12 to 56% by weight P.sub.2 O.sub.5 1 to 27% by weight SiO.sub.2 22 to 50% by weight MgO 0 to 34% by weight Al.sub.2 O.sub.3 0 to 25% by weight ______________________________________
- in a total amount of at least 90%;
- a second step of preparing crystallized glass by heat-treating the glass obtained in the first step in a temperature range in which there are precipitated a crystal of apatite and at least one crystal of alkaline earth metal silicate selected from the group consisting of wollastonite, diopside, forsterite, akermanite and anorthite;
- a third step of preparing mixture powder by mixing the crystallized glass obtained by the second step with partially stabilized zirconia powder and/or alumina powder while grinding the crystallized glass or after grinding the crystallized glass;
- and
- a fourth step of preparing an inorganic biomaterial of a ceramics/crystallized glass composite by molding the mixture powder obtained by the third step into a desired shape and then heat-treating the resulting molding in a temperature range in which the partially stabilized zirconia and/or alumina powder is sintered.
A process for producing an inorganic biomaterial, which comprises:
- a first step of sintering a crystal of calcium phosphate at a temperature in a range of from 800.degree. to 1400.degree. C. to thereby prepare a calcium phosphate crystal sintered body;
- a second step of grinding the sintered body obtained in the first step to thereby prepare powder of the sintered body, and, at the same time of or after preparation of the powder of the sintered body, mixing the prepared powder of the sintered body with partially stabilized zirconia powder and/or alumina powder to thereby prepare mixture powder;
- and
- a third step of molding the mixture powder obtained in the second step into a desired shape and heat-treating the resulting molding in a temperature range in which the partially stabilized zirconia and/or alumina powder is sintered.
Dependencies are inferred from the claim text.