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US 5,231,000 AGranted
Antibodies to A4 amyloid peptide
AssigneesThe McLean Hospital Corporation, University of Rochester
InventorsRon Majocha, Charles A. Marotta, Sayeeda Zain
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Abstract
Monoclonal antibodies to a 28-mer peptide present within A4-amyloid are described. These antibodies exhibit unexpected specificity for amyloid plaque structures previously unrecognized in Alzheimer's disease brains. These monoclonal antibodies are useful as reagents for use in assays and imaging of A4-amyloid in Alzheimer's disease patients.
Claims9
Hybridoma cell line ATCC HB9542.
An antibody expressed from the hybridoma cell line 10H3 which is deposited at the ATCC under accession no. HB9542.
Dependencies are inferred from the claim text.