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US 5,225,183 AGranted
Medicinal aerosol formulations
AssigneeRiker Laboratories, Inc.
InventorsTarlochan S. Purewal, David J. Greenleaf
Life of this patent
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Abstract
A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
Claims3
An aerosol formulation comprising:
- (a) a therapeutically effective amount of a medicament;
- (b) a propellant substantially free of chlorofluorocarbons, said propellant comprising 1,1,1,2-tetrafluoroethane;
- (c) a surface active agent in an amount sufficient (i) to stabilize the formulation or (ii) lubricate a valve stem in a metering valve;
- and
- (d) at least one compound selected from the group consisting of ethyl alcohol, isopropyl alcohol, n-pentane, isopentane, neopentane, isopropyl, and myristate, said compound being present in an amount such that it is miscible with the 1,1,1,2-tetrafluoroethane and such that said surface active agent is soluble in the formulation in a greater amount than in 1,1,1,2-tetrafluoroethane.
2 more elements
Dependencies are inferred from the claim text.