US 5,223,625 AGranted

Annelated indolo [3,2,-C]lactams

AssigneeDuphar International Research B.V.

InventorsIneke Van Wijngaarden, Hans H. Haeck, Derk Hamminga, Wouter Wouters

Life of this patent

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Abstract

The invention relates to a group of new annelated indolo [3,2-c] lactam derivatives of the formula ##STR1## having an antagonistic activity on 5-HT receptors. The compounds can be used for the treatment of symptoms which are caused by excessive stimulation of said receptors in the gastrointestinal system, the central nervous system, the cardiovascular system, the respiratory system, and for alleviating or preventing withdrawal symptoms which are induced by abuse of drugs.

Claims2

Dependent claims

A compound having the formula:

##STR30##

Dependencies are inferred from the claim text.

Facts

Application: 07/913,901Filed 16 Jul 1992 · division
Priority: NL 880313522 Dec 1988
Granted: 29 Jun 1993
Term ends: Not estimatedThe source records don’t support an estimate.

Classification5 codes

C07D 471/16
In which the condensed system contains three hetero rings: peri-condensed systems
C07D 487/16
In which the condensed system contains three hetero rings: peri-condensed systems
C07D 513/16
In which the condensed system contains three hetero rings: peri-condensed systems
C07D 519/00
Heterocyclic compounds containing more than one system of two or more relevant

Family

Serial452,501Parent of this division · filed 19 Dec 1989
US 5,223,625 AThis patent

From the US filing history. Foreign family members aren’t listed.

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