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US 5,221,724 AGranted
Polysiloxane polyurea urethanes
AssigneeWisconsin Alumni Research Foundation
InventorsChi Li, Stuart L. Cooper
Life of this patent
Estimating the term…
Abstract
Polysiloxane-containing polyurea and polyurea urethane block copolymers and devices formed therefrom are biocompatible and demonstrate improved physical and mechanical properties. The pre-reaction of an amine-terminated polysiloxane soft segment with an organic diisocyanate provides an oligomer that enhances the hydrophilic properties of the copolymer.
Claims34
A polysiloxane-containing block copolymer based on:
- (a) an oligomer comprising the reaction product of
- (i) a linear aliphatic diisocyanate;
- and
- (ii) a molar excess relative to said aliphatic diisocyanate of a polysiloxane represented by the formula:
- ##STR2## wherein n is an integer from 1 to about 200,
- R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently selected monovalent linear, branched or cyclic aliphatic or aromatic hydrocarbon radicals, including substituted or unsubstituted hydrocarbon radicals, containing from 1 to about 16 carbon atoms each, and
- R.sub.5 and R.sub.6 are independently selected divalent linear branched or cyclic aliphatic or aromatic hydrocarbon radicals, including substituted or unsubstituted hydrocarbon radicals, containing from 1 to about 16 carbon atoms each;
- (b) an organic diisocyanate;
- and
- (c) an independently selected C.sub.2 -C.sub.20 alkyl diol, C.sub.2 -C.sub.20 aryl diol, C.sub.2 -C.sub.20 alkyl diamine or C.sub.2 -C.sub.20 aryl diamine.
7 more elements
A method for the production of a polysiloxane-containing polyurea urethane or polyurea block copolymer comprising:
- (a) providing an oligomer that comprises the reaction product of:
- (1) a linear aliphatic diisocyanate;
- and
- (2) a molar excess relative to said diisocyanate of a polysiloxane represented by the formula:
- ##STR3## wherein n is an integer from 1 to about 200,
- R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently selected monovalent linear, branched or cyclic aliphatic or aromatic hydrocarbon radicals, including substituted or unsubstituted hydrocarbon radicals, containing from 1 to about 16 carbon atoms each, and
- R.sub.5 and R.sub.6 are independently selected divalent linear branched or cyclic aliphatic or aromatic hydrocarbon radicals, including substituted or unsubstituted hydrocarbon radicals, containing from 1 to about 16 carbon atoms each;
- (b) admixing an organic diisocyanate with the oligomer of (a);
- and
- (c) admixing an independently selected C.sub.2 -C.sub.20 alkyl diol, C.sub.2 -C.sub.20 aryl diol, C.sub.2 -C.sub.20 alkyl diamine or C.sub.2 -C.sub.20 aryl diamine with the mixture of (b).
7 more elements
An oligomer comprising the reaction product of:
- (a) an organic linear aliphatic diisocyanate;
- and
- (b) a molar excess relative to said aliphatic diisocyanate of a polysiloxane represented by the formula:
- ##STR4## wherein n is an integer from 1 to about 200;
- R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are independently each selected from linear, branched or cyclic aliphatic or aromatic hydrocarbon radicals, including substituted or unsubstituted hydrocarbon radicals, containing from 1 to about 8 carbon atoms each;
- and
- R.sub.5 and R.sub.6 are independently selected from linear, branched or cyclic aliphatic or aromatic hydrocarbon radicals, including substituted or unsubstituted hydrocarbon radicals, containing from 1 to about 16 carbon atoms.
4 more elements
Dependencies are inferred from the claim text.