Process for preparing fatty acid esters
AssigneeYoshikawa Oil & Fat Co., Ltd.
InventorsKatsunori Myojo, Youichi Matsufune, Shiro Yoshikawa
Life of this patent
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Abstract
A process for reacting (1) a component selected from the group consisting of sterols and branched aliphatic primary or secondary alcohols having 14 to 32 carbon atoms, and (2) a component selected from the group consisting of fatty acids and fatty acid esters in contact with an enzyme selected from the group consisting of lipase and cholesterol esterase or with the selected enzyme in an immobilized form, in a system selected from the group consisting of an aqueous medium and water-containing organic solvent to prepare a fatty acid ester of the component (1).
Claims57
A process for preparing a fatty acid ester, the process consisting essentially of reacting:
- (1) a component selected from the group consisting of cholesterol, .beta.-sitosterol, stigmasterol, .beta.-cholesterol, ergosterol, isocholesterol, campesterol, brassicasterol and isotridecyl alcohol and
- (2) a component selected from the group consisting of fatty acids and fatty acid esters,
- in contact with a lipase derived from a microorganism selected from the group consisting of Candida cylindracea, Pseudomonas fluorescens, Pseudomonas fragi, Chromobacterium viscosum, Aspergillus niger, and Rhizopus delemar, in a reaction system consisting essentially of the component (1), the component (2), the lipase, and either water or a water-containing organic solvent,
- and recovering the product fatty acid ester from the resulting mixture.
A process as defined in 1 wherein the component (2) is a glycerin ester of a fatty acid having up to 32 carbon atoms.
A process as defined in 1 wherein the component (2) is an ester of aliphatic alcohol having 1 to 14 carbon atoms.
A process as defined in 1 wherein the reaction is conducted in a water-containing organic solvent.
A process as defined in 1 wherein the water-containing organic solvent is capable of dissolving at least one of component (1) and component (2) and is an organic solvent containing water to at least saturation.
A process for preparing a fatty acid ester, which comprises reacting a component (1) and a component (2) in contact with a cholesterol esterase in a reaction system consisting essentially of said component (1), said component (2), said cholesterol esterase and a water-containing organic solvent, wherein
- component (1) being at least one member selected from the group consisting of cholesterol, isocholesterol, campesterol, stigmasterol, .beta.-sitosterol, brassicasterol, .beta.-cholestanol, 2-octyldodecanol, Lanolin alcohol HH and a branched aliphatic saturated alcohol represented by the following formula:
- ##STR8## component (2) being at least one member selected from the group consisting of fatty acids and fatty acid esters in contact with a cholesterol esterase derived from Candida cylindracea, and
- recovering the product fatty acid ester from the resulting mixture.
A process for preparing a fatty acid ester, which comprises reacting a component (1) and a component (2) in contact with a cholesterol esterase in a reaction system consisting essentially of said component (1), said component (2), said cholesterol esterase and a water-containing organic solvent, wherein
- component (1) being at least one member selected from the group consisting of cholesterol, .beta.-sitosterol, isocholesterol, campesterol, stigmasterol, .beta.-sitosterol, brassicasterol, .beta.-cholestanol, 2-octyldodecanol, Lanolin alcohol HH and a branched aliphatic saturated alcohol represented by the following formula:
- ##STR9## component (2) being at least one member selected from the group consisting of fatty acids and fatty acid esters in contact with cholesterol esterase T-18, and
- recovering the product fatty acid ester from the resulting mixture.
A process for preparing a fatty acid ester, which comprises reacting a component (1) and a component (2) in contact with a cholesterol esterase in a reaction system consisting essentially of component (1), said component (2), said cholesterol esterase and a water-containing organic solvent, wherein
- 2-octyldodecanol as a component (1) is reacted with a component (2) selected from the group consisting of capric acid and oleic acid in contact with a panaceas-derived cholesterol esterase,
- and recovering the product fatty acid ester from the resulting mixture.
Dependencies are inferred from the claim text.