Substituted fluorobenzenes
AssigneeImperial Chemical Industries PLC
InventorsJohn S. Moilliet, Richard D. Chambers, Michael H. Rock
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Abstract
Introduction of a fluoro substituent into an aromatic ring adjacent an electron donating group is difficult producing mixed isomers and low yields of desired products. A process for the introduction of a fluoro substituent into a substantially adjacent position to an electron-donating group into an aromatic compound in high yield is disclosed. The fluoroaromatic compounds are useful as synthetic intermediates for example in the manufacture of agrochemicals, pharmaceuticals and dyestuffs.
Claims6
A process for the preparation of a 3-fluoroaromatic compound by reacting an aromatic compound which carries an electron-withdrawing group in the 1-position and an electron-donating group in the 4-position with a gas comprising a mixture of fluorine and an inert gas containing up to 50% fluorine by volume.
Dependencies are inferred from the claim text.