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US 5,212,178 AGranted
8.alpha.-acylamino ergolines and use as pharmaceutical agents
AssigneeSchering Corporation
InventorsGerhard Sauer, Thomas Brumby, Helmut Wachtel, Jonathan Turner, Peter-Andreas Loschmann
Life of this patent
Estimating the term…
Abstract
8.alpha.-acylamino ergolines are useful dopamine agonists.
Claims12
A compound of Formula I ##STR8## in which CC each independently is a single or double bond;
- R.sup.2 is optionally substituted C.sub.1-7 -alkyl, or C.sub.2-7 -alkenyl, CH.sub.2 --O--C.sub.1-4 -alkyl, or CH.sub.2 --S--C.sub.1-4 -alkyl;
- R.sup.6 is C.sub.2-6 alkyl, C.sub.3-6 -alkenyl, or C.sub.3-5 -cycloalkyl-C.sub.1-2 -alkyl;
- R.sup.8 is --CXR.sup.3,
- R.sup.3 is hydrogen or optionally substituted C.sub.1-6 -alkyl;
- or a pharmaceutically acceptable acid addition salt thereof.
2 more elements
Dependencies are inferred from the claim text.