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AssigneePuritan-Bennett Corporation
InventorsJeffrey T. Jackson, Henry K. Hui
Estimating the term…
The solution for storage and calibration of an intravascular blood sensor is an aqueous solution of from 10-35 mM of a first buffer component of bicarbonate, and at least one additional buffer component selected to maintain the pH of the solution substantially at or slightly below a neutral pH, and preferably below approximately pH 8. The first and additional buffering components preferably are selected to act in two separate pH regions with substantially no overlap of the buffering capacity of the different buffering components, and the concentration of the first buffer component in the solution is selected to permit a two point calibration of the intravascular multiparameter blood sensor by carbon dioxide and oxygen gas tonometry.
A method for calibrating an intravascular blood sensor in a solution for storage and calibration of an intravascular multiparameter blood sensor buffered to maintain the pH of the solution without loss of the gas tonometric properties of the solution following steam sterilization of the solution, the solution comprising an aqueous solution of from 10-35 mM of a first buffer component selected from the group consisting of bicarbonate and carbonate salts and at least one additional buffer component selected to maintain the pH of the solution at or below a pH of approximately 8, the steps of the method comprising:
A method for calibrating an intravascular blood sensor in a solution for storage and calibration of an intravascular multiparameter blood sensor buffered to maintain the pH of the solution without loss of the gas tonometric properties of the solution following steam sterilization of the solution, the solution comprising an aqueous solution of from 10-35 mM of a first buffer component selected from the group consisting of bicarbonate and carbonate salts and at least one additional buffer component selected to maintain the pH of the solution at or below approximately neutral pH, said first and additional buffering components acting in two separate pH regions with substantially no overlap of the buffering capacity of the different buffering components, the steps of the method comprising:
Dependencies are inferred from the claim text.