SF-25 Colon adenocarcinoma antigen, and antibodies with recognize this antigen
AssigneeThe General Hospital Corporation
InventorsJack R. Wands, Hiroshi Takahashi
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Abstract
The present invention pertains to the SF-25 antigen of colon adenocarcinoma cells, to functional derivatives of this antigen, and to antibodies and antibody fragments capable of binding this antigen. The invention further discloses methods of diagnosing and treating colon cancer which employ the above molecules.
Claims12
A molecule which specifically binds to the SF-25 antigen of a colon adenocarcinoma cell, said molecule being selected from the group consisting of:
- (a) an antibody substantially free of natural contaminants;
- (b) a monoclonal antibody;
- (c) a fragment of (a) or (b).
A hybridoma cell line which secretes a monoclonal antibody, said antibody specifically binding to the SF-25 antigen of a colon adenocarcinoma cell.
Dependencies are inferred from the claim text.