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US 5,212,065 AGranted
Rapid assay device
AssigneesInternational Diagnostic Systems, Corp., KM Laboratories, Inc.
InventorsR. Kevin Pegg, Mary S. Saunders
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Abstract
A rapid immunoassay device comprising a single porous membrane that serves as both a reagent support and a spent reagent reservoir is disclosed. The immunoassay device directs the flow of sample and reagents within the device in a manner that eliminates both lateral diffusion and backflow of reagents without the necessity of additional external means.
Claims28
An apparatus for use in immunoassay procedures consisting essentially of:
- (A) a housing comprising a reservoir member and a base member, said reservoir member defining a cavity, said base member engaging said reservoir member to enclose said cavity, and having
- (i) a first surface on said reservoir member facing away from said cavity and a second surface on said reservoir member facing into said cavity;
- (ii) an aperture providing an opening through both of said first and second surfaces,
- (iii) a first profile provided on said first surface around said aperture,
- (iv) at least one vent hole,
- (v) a second profile facing said cavity provided on said second surface around said aperture;
- (B) a single porous foam member provided in said cavity, wherein a surface of said foam member is deformable by said second profile to produce a depression that surrounds an area on said surface of said foam member;
- and
- (C) a reagent-binding member provided on said surface of said member, wherein no external means to direct the flow of sample and reagents within said apparatus is required.
6 more elements
Dependencies are inferred from the claim text.