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US 5,211,960 AGranted
Stabilization of leukocytes
AssigneeScripps Clinic and Research Foundation
InventorBernard M. Babior
Life of this patent
Estimating the term…
Abstract
Preservation of leukocytes by suspending in storage medium containing modified fluid gelatin, plasma, and a non-toxic buffer. Preferred additives include heterocyclic bases which occur in nucleic acids, or nucleosides or nucleotides containing the same.
Claims6
A stock solution adapted to be mixed with a suspension of human leukocytes to maintain function during storage, said solution comprising a
- water solution containing an amount of modified fluid gelatin from 8% by weight up to the amount causing the solution to gel at room temperature, and
- a member of the group consisting of a) the heterocyclic bases which occur in nucleic acids, b) nucleosides containing said bases, c) nucleotides containing said bases, and d) mixtures of a), b) and c), said member being present at a concentration from 0.5 micromolar to 20 millimolar.
Dependencies are inferred from the claim text.