Process for nitrating benzocyclobutene compounds
AssigneeThe Dow Chemical Company
InventorsP. J. Thomas, R. Garth Pews
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Abstract
An improved process for the nitration of a substituted or unsubstituted benzocyclobutene compound in a reaction mixture comprising a nitrating agent, an unhalogenated carboxylic acid anhydride, clay and a solvent to produce a corresponding nitrobenzocyclobutene compound, is that wherein: (a) the solvent has a density above that of the nitrating agent or an extractable precursor thereof; (b) the reaction mixture is heated at a temperature such that solvent is removed from the reaction mixture to a site outside the reaction mixture to extract nitrating agent or extractable precursor thereof; and (c) the thus-extracted nitrating agent or precursor thereof is fed into the reaction mixture to nitrate the benzocyclobutene compound.
Claims21
A process for the nitration of a substituted or unsubstituted benzocyclobutene compound in a reaction mixture comprising a nitrating agent, an unhalogenated carboxylic acid anhydride, clay and a solvent to produce a corresponding nitrobenzocyclobutene compound, wherein:
- (a) the solvent has a density above that of the nitrating agent or an extractable precursor thereof;
- (b) the reaction mixture is heated at a temperature such that solvent is removed from the reaction mixture to a site outside the reaction mixture to extract nitrating agent or extractable precursor thereof;
- and
- (c) the thus-extracted nitrating agent or precursor thereof is fed into the reaction mixture to nitrate the benzocyclobutene compound.
A process for the nitration of a substituted or unsubstituted benzocyclobutene compound, comprising nitrating the benzocyclobutene compound with copper nitrate-loaded clay in a solvent inert to reactants or products in the presence of an unhalogenated carboxylic acid anhydride.
Dependencies are inferred from the claim text.