Ouinone derivatives and pharmacological use

A quinone derivative represented by the following general formula and pharmacologically acceptable salts thereof:

• ##STR242## wherein R.sup.1 is an alkyl group having 2 to 20 carbon atoms, a cycloalkyl group, a cycloalkylalkyl group, an alkenyl group, an alkynyl group, an arylalkyl group, a group represented by the formula --(--CH.sub.2 --).sub.p --CN, p being an integer of 1 to 10, a morpholine group, a piperazine group, a thiotolene group, a methyltetrahydropyran group, a methylthiazole group, a piperidine group or a 2-aminothiazole group, a group represented by the formula --(--CH.sub.2 --).sub.q --B, q being an integer of 1 to 6 and B being a group of the formula ##STR243## with r being 0, 1 or 2 and R.sup.7 being a lower alkyl group, a cycloalkyl group or an aryl group, a group represented by the formula --O--R.sup.11, R.sup.11 being a lower alkyl group or an aryl group, or a group represented by the formula --(--CH.sub.2 --CH.sub.2 --O--).sub.s --CH.sub.3, s being an integer of 1 to 3;
• R.sup.2 is a group represented by the --OR.sup.8, R.sup.8 being a hydrogen atom or a lower alkyl group, or a group represented by the formula ##STR244## R.sup.9 and R.sup.10 being the same or different from each other and each being a hydrogen atom, a lower alkyl group, a hydroxyalkyl group, a morpholine group, a piperazine group, a thiotolene group, a methyltetrahydropyran group, a methylthiazole group, a piperidine group or a 2-amino thiazole group, or R.sup.9 and R.sup.10 may combine with each other to form a heterocyclic group with the adjacent nitrogen atom, said heterocyclic group optionally being substituted;
• and R.sup.3, R.sup.4 and R.sup.5 are the same or different from each other and each are a hydrogen atom, a lower alkyl group or a lower alkoxy group.