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US 5,210,222 AGranted
Process for the production of malonic acid anhydride
AssigneeLonza Ltd.
InventorColm O'Murchu
Life of this patent
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Abstract
A process, which is harmless with respect to safety, for the production of malonic acid anhydride. For this purpose, diketene is ozonized in the presence of a suitable carbonyl compound. Malonic acid anhydride is a highly reactive intermediate product for the synthesis of numerous active ingredients for, e.g., pharmaceutical agents, pesticides or dyes.
Claims12
Process for the production of malonic acid anhydride of the formula:
- ##STR7## characterized in that diketene is ozonized at a temperature between -30.degree. and -100.degree. C. in the presence of a carbonyl compound of formula:
- ##STR8## wherein R.sub.1 and R.sub.2 are the same or different and are hydrogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group which is methoxy or ethoxy, or an aryl group which is phenyl or p-toluyl.
Dependencies are inferred from the claim text.