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US 5,210,212 AGranted
Process for 5-fluoro-6-chlorooxindole
AssigneePfizer Inc.
InventorRobert W. Dugger
Life of this patent
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Abstract
Process for the production of 5-fluoro-6-chloro- oxindole, (III), which is useful in the synthesis of certain analgesic and antiinflammatory agents, via two different synthetic pathways. Compounds of formula (I) and (II) shown below ##STR1## which are intermediates in the process of this invention.
Claims5
A process for the preparation of a compound of the formula ##STR6## which comprises of rearranging a compound of the formula ##STR7## with a hydrogen fluoride source in the presence of an alkyl or aryl nitrile to produce compound (III).
Dependencies are inferred from the claim text.