Use of pyruvate to treat acute renal failure
AssigneeRegents of the University of Minnesota
InventorKarl A. Nath
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Abstract
A therapeutic method is provided to arrest or prevent acute kidney failure by administration of a non-toxic pyruvate salt to a patient in need of such treatment.
Claims11
A therapeutic method comprising parenterally administering an amount of a pyruvate salt to a patient experiencing the abrupt decline in renal function associated with acute renal failure, which amount is effective to treat said renal failure.
A method comprising treating repersion injury to an isolated, ischemic human kidney following reimplantation into a human recipient by perfusing said kidney with with an aqueous solution comprising an effective protectant amount of a pyruvate salt.
Dependencies are inferred from the claim text.