Xanthocillin X monomethyl ether derivative and antitumor agent containing the same
AssigneeMeiji Seika Kaisha, Ltd.
InventorsHiroshi Kurihara, Hiromi Watanabe, Masao Koyama, Masaji Sezaki, Tsutomu Tsuruoka, Harumi Fukuyasu, Haruo Yamamoto
Life of this patent
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Abstract
A xanthocillin X monomethyl ether derivative represented by the formula (I) ##STR1## wherein R represents an alkyl group, an alkenyl group, an alkoxycarbonyl group, an aralkyl group, an alkyl group substituted with a pyridyl group or a halogen atom, an aralkyl group substituted with an alkyl group or a halogen atom, or an aroyl group, which exerts an intense effect of inhibiting the proliferation of a tumor, in particular, a solid tumor.
Claims3
A xanthocillin X monomethyl ether derivative represented by the following formula (I):
- ##STR4## wherein R represents (a) a propenyl group (b) an ethoxycarbonyl group (c) a benzyl group, (d) an ethyl group substituted with a halogen atom, (e) a benzyl group substituted with a methyl group or a halogen atom, or (f) a benzoyl group.
Dependencies are inferred from the claim text.