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US 5,210,096 AGranted
Antiviral compositions and method for their use
AssigneeChai-Tech Corporation
InventorDavid I. Scheer
Life of this patent
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AssigneeChai-Tech Corporation
InventorDavid I. Scheer
Estimating the term…
Compositions having significant activity as antiviral agent are disclosed containing, as an active component, a compound having the structural formula: ##STR1## wherein R.sub.1 and R.sub.1' are the same or different and each is an alkyl group, a phenyl group or a substituted derivative of a phenyl group; wherein R.sub.2 and R.sub.2' are the same or different and each is hydrogen, an unbranched alkyl group, a halide or a group having the structure ##STR2## wherein R is hydrogen, an alkoxide group, an alkyl group, or OH; wherein R.sub.3 and R.sub.3' are the same or different and each is hydrogen or an alkyl group; wherein X and X' are the same or different and each is a water soluble group having weak to intermediate ligand field strength; and Q.sup.- is a soluble, pharmaceutically acceptable negative ion. Methods of use of the inventive compositions are also disclosed.
An antiviral composition comprising a suitable carrier and a compound in anti-herpesvirus effective amount, the compound having the structure ##STR9## wherein R.sub.1 and R.sub.1, are the same or different and each is an alkyl group, a phenyl group or a substituted derivative of a phenyl group;
An antiviral composition comprising a suitable carrier and a compound in an anti-adenovirus effective amount, the compound having the structure ##STR11## wherein R.sub.1 and R.sub.1, are the same or different and each is an alkyl group, a phenyl group or a substituted derivative of a phenyl group;
An antiviral composition comprising a pharmaceutically acceptable carrier and a complex in an anti-herpes effective amount, the complex comprising a Co(III) complex having an octahedral basal plane defined by four donor atoms A, which may be the same or different, and two axial ligand donor atoms B, which may be the same or different, said donor atoms having a ligand field strength equal to or less than CN.sup.-, said complex reacting with O.sub.2.sup.- to form a Co(III)-O.sub.2 adduct or oxidizing O.sub.2.sup.- to produce dioxygen and a Co(II) complex.
An antiviral composition comprising a pharmaceutically acceptable carrier and a complex in an anti-adenovirus effective amount comprising a Co(III) complex having an octahedral basal plane defined by four donor atoms A, which may be the same or different, and two axial ligand donor atoms B, which may be the same or different, said donor atoms having a ligand field strength equal to or less than CN.sup.-, said complex reacting with O.sub.2.sup.- to form a Co(III)-O.sub.2 adduct or oxidizing O.sub.2.sup.- to produce dioxygen and a Co(II) complex.
Dependencies are inferred from the claim text.