Substituted N-benzylpiperidine amides and cardiac regulatory compositions thereof

A compound of the formula ##STR173## the pharmaceutically acceptable nontoxic salts thereof or the hydrated forms thereof, wherein R.sup.1 is substituted or unsubstituted benzofuranyl wherein said substituent is alkylsulfonamido wherein the alkyl portion is 1 to 4 carbon atoms with the proviso that R.sup.1 is unsubstituted benzofuranyl only when ##STR174## is alkyl sulfonamido substituted phenyl;

• n is an integer of from one to ten;
• R.sup.2 is unsubstituted or is alkyl of from one to ten carbon atoms or oxygen that is present as an N-oxide;
• R.sup.3 is hydrogen, carboxyalkyl of from one to ten carbon atoms or alkoxycarbonylalkyl of from one to ten carbon atoms;
• ##STR175## is hydrogen;
• pyridinyl;
• cycloalkyl of three to eight carbon atoms or hydroxy substituted cycloalkyl of three to eight carbon atoms;
• furanyl;
• or unsubstituted or substituted phenyl wherein said phenyl substituent is one or more of alkyl, halogen substituted alkyl of one to ten carbon atoms, alkoxy from one to ten carbon atoms, nitro, amine, mono or dialkylamine, acetyl amine, acetylamide, halogen, alkylsulfonamido wherein the alkyl portion is 1 to 4 carbon atoms, alkoxy itself substituted by halogen substituted phenyl.