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AssigneeTaisho Pharmaceutical Co., Ltd.
InventorsTadashi Kosaka, Kazuki Omata, Tatsuo Hashimoto, Teruaki Yamazaki, Kazuo Hayashi, Tomiya Hosoi, Kenichi Ikuta
Estimating the term…
A soft capsule composed of a plurality of cells coalesced to each other and filling substances encapsulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least one of the other cells, and said capsule being seamless. The soft capsule can be produced by (a) preparing a plurality of composite jet streams each consisting of a stream of a film-forming liquid substance for forming a cell wall and within said stream of a film-forming liquid substance a single stream, or a plurality of independent streams, of a filling substance having flowability, the film-forming liquid substance in at least one of the composite jet streams being different from the film-forming liquid substance in at least one of the other composite jet streams, (b) advancing the plurality of composite jet streams in closely spaced relationship into and through a stream of a liquid medium substantially incapable of dissolving the film-forming liquid substance in the flowing direction of the liquid medium stream, (c) coalescing the adjacent composite jet streams to each other to form a single composite jet stream in the liquid medium stream, (d) cutting the single composite jet stream to a predetermined length successively from its leading end in the liquid medium stream, and (e) solidifying the cell walls of the resulting soft capsule.
A process for producing a soft capsule composed of a plurality of cells coalesced to each other and filling substances encapsulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least a second of the cells, and said capsule being seamless, said method comprising:
A unitary seamless capsule containing plural cells coalesced together, each of said cells containing a filling substance encapsulated by a cell wall completely surrounding the filling substance, the cell wall of at least one of the cells being formed of a material different from a material forming the wall of at least a second of said cells, said cell walls being melded together with each of said cell walls defining in part the outermost surface of said seamless capsule, said capsule having one cross-section cutting through all of said plural cells.
Dependencies are inferred from the claim text.