Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
OwnerEvan C. Ungerinventor
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Abstract
Gas filled liposomes prepared by a vacuum drying gas instillation method and/or gas filled liposomes substantially devoid of liquid in the interior thereof, are presented as novel potentiators for ultrasonic hyperthermia. The liposomes of the present invention, which may be administered into the vasculature, interstitially or into any body cavity are designed to accumulate in cancerous and diseased tissues. When therapeutic ultrasonic energy is applied to the diseased region heating is increased because of the greater effectiveness of sound energy absorption caused by these agents.
Claims16
A method for heat treating biological tissues and fluids which comprises:
- (i) administering to the tissue or fluid to be treated a therapeutically effective amount of a hyperthermia potentiator comprising gas filled liposomes prepared by a vacuum drying gas instillation method;
- and
- (ii) applying ultrasound to said tissue or fluid.
A method for heat treating biological tissues and fluids which comprises:
- (i) administering to the tissue or fluid to be treated a therapeutically effective amount of a hyperthermia potentiator comprising gas filled liposomes substantially devoid of liquid in the interior thereof;
- and
- (ii) applying ultrasound to said tissue or fluid.
Dependencies are inferred from the claim text.