Method and device for local application and removal of active substances against solid tumors
AssigneePharma Biotechnologie Hannover GmbH
InventorsHans-Joachim Schmoll, Ekkehard Schmoll, Edmund R. Lax
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Abstract
Described are a method and a device for the application and the removal of locally applied active substances against solid tumors, which device consists of a catheter (1) to be positioned distally to the tumor for the collection of blood coming from the tumor, a pump (2) and a catheter (3) connected thereto and returning the blood into the body. The device is characterized in that between the two catheters (1, 3) there is present at least one container (4) capable of allowing blood to pass therethrough and containing immobilized substances having high affinity against the applied active substance.
Claims12
A method for the treatment of solid tumors, wherein a therapeutically effective amount of active substances against the solid tumors are locally injected, characterized in that (a) the active substance is infused into an afferent blood vessel of a tumor-containing organ, (b) a second active substance, which is capable to inactivate the effect of the first active substance, is infused distally to the tumor-containing organ, and (c) both active substances are filtered out of the patient's blood, wherein the blood is withdrawn distally to the tumor, pumped through a container containing substances, which are capable to bind the active substances, and returning the blood into the patient's body.
Dependencies are inferred from the claim text.