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US 5,208,345 AGranted
Process for the production of (S)-vinyl and allenyl gaba
AssigneeMerrell Dow Pharmaceuticals Inc.
InventorJonathan C. Evans
Life of this patent
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Abstract
The present invention is directed to a new class of pyrrolidinone derivatives that are useful as chemical intermediates in the synthesis of S-allenyl and S-vinyl GABA, both of which are antiepileptic agents.
Claims9
An optical isomer of the formula:
- ##STR21## in which A is represented by --CH.dbd.CH.sub.2 or --CH.dbd.C.dbd.CH.sub.2, and X and Y are each simultaneously represented by
- ______________________________________ Y X ______________________________________ ##STR22## ##STR23## ##STR24## H ##STR25## H ##STR26## ______________________________________
An optical isomer of the formula:
- ##STR27## in which A is represented by --CH.dbd.CH.sub.2 or --CH.dbd.C.dbd.CH.sub.2, and X and Y are each simultaneously represented by
- ______________________________________ Y X ______________________________________ ##STR28## H ##STR29## H ##STR30## ______________________________________
Dependencies are inferred from the claim text.