Tetrahydropyridine oxime compounds

A compound of the formula ##STR5## wherein the dotted line indicates a bond between either the carbons at the 3- and 4-positions or the 4- and 5-positions;

• wherein the side chain ##STR6## is attached to either the 3- or 4-position of the tetrahydropyridine ring;
• wherein R.sup.1 is hydrogen;
• a straight or branched alkyl group having from 1 to 6 carbon atoms;
• a cycloalkylmethyl group wherein the cycloalkyl moiety has from 3 to 6 carbon atoms;
• phenyl(CH.sub.2).sub.n wherein n is one or two and wherein the phenyl ring is unsubstituted or is substituted with from 1 to 3 substituents selected from chlorine, bromine, fluorine, trifluoromethyl, hydroxy, straight or branched alkoxy having from 1 to 4 carbon atoms, straight or branched alkyl having from 1 to 4 carbon atoms, trifluoromethoxy, nitro, or --NR.sub.3 R.sub.4 wherein each of R.sub.3 and R.sub.4 is individually hydrogen or a straight or branched alkyl having from 1 to 4 carbon atoms;
• wherein Ar is 2- or 3-thienyl, phenyl, or phenyl substituted with from 1 to 3 substituents selected from chlorine, bromine, fluorine, trifluoromethyl, hydroxy, straight or branched alkoxy having from 1 to 4 carbon atoms, straight or branched alkyl having from 1 to 4 carbon atoms, trifluoromethoxy, nitro, or --NR.sub.3 R.sub.4 wherein each of R.sub.3 and R.sub.4 has the meaning defined above;
• wherein R.sub.2 hydrogen, a straight or branched alkyl having from 1 to 6 carbon atoms, benzyl, or phenethyl;
• a pharmaceutically acceptable salt thereof or a geometric and optical isomer thereof.