Back to results
US 5,208,327 AGranted
Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine
AssigneeOrtho Pharmaceutical Corporation
InventorRobert H. K. Chen
Life of this patent
Estimating the term…
Abstract
This invention relates to a novel process for preparing 2-chloro-2'-deoxyadenosine (2-CdA) having the following formula ##STR1## from a compound of the following formula ##STR2## The invention also relates to intermediates which are useful in preparing 2-CdA. The compound 2-CdA is useful as an antileukemic agent, i.e., in treating leukemias, such as hairy cell leukemia.
Claims3
A compound of the following formula ##STR12##
A compound of the following formula ##STR13## wherein Z is R.sup.2 or YR.sup.2 ;
- Y is O or S;
- and R.sup.2 is a C.sub.1-5 straight- or branched-chain alkyl or phenyl.
A compound of the following formula ##STR14##
Dependencies are inferred from the claim text.