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US 5,208,263 AGranted
Anti-androgen compounds
AssigneeArch Development Corporation
InventorsShutsung Liao, John Pataki, Ronald G. Harvey
Life of this patent
Estimating the term…
Abstract
Disclosed are novel classes of anti-androgen including dihydrophenanthrene derivatives, their method of synthesis and their use in treating disorders associated with excessive androgenic activities.
Claims1
A method for treatment of disorders associated with excessive androgenic activity comprising administering a pharmaceutical composition which includes an anti-androgenic compound selected from the group consisting of the general formula:
- ##STR16## wherein ring A is 2-substituted with a hydroxyl, a 1'-hydroxyethyl or a 2' hydroxyethyl;
- ring B is monounsaturated at the 9-10 position and is optionally substituted with methyl at either the 9 or 10 position;
- and ring C is unsubstiuted, provided that rings A and C may not both be unsubstituted.
Dependencies are inferred from the claim text.