Stabilized mercuric oxide ointment compositions
AssigneeDel Laboratories, Inc.
InventorsHarry Gordon, Henry Chan, Howard Brasch
Life of this patent
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Abstract
Oleaginous ointment compositions for topical antibacterial treatment containing about 0.5 to about 1.5% yellow mercuric oxide by weight and additionally containing organic acids selected from the group consisting of alkanoic acids of formula CH.sub.3 (CH.sub.2).sub.n COOH, wherein n is an integer from 4 to 22, and arylalkanoic acids of formula C.sub.6 H.sub.5 (CH.sub.2).sub.n COOH, wherein n is an integer from 0 to 17, to increase the color stability of the compositions. A method of making the novel stabilized ointment compositions is also disclosed.
Claims23
An oleaginous ointment composition for topical antibacterial treatment containing about 0.5 to about 1.5% yellow mercuric oxide by weight of the composition, wherein the improvement comprises increasing the color stability of the composition by the addition thereto of about 0.1 to about 10.0% by weight of a stabilizing compound selected from the group consisting of alkanoic acids of formula CH.sub.3 (CH.sub.2).sub.n COOH, wherein n is an integer from 4 to 22, benzoic acid and arylalkanoic acids of formula C.sub.6 H.sub.5 (CH.sub.2).sub.n COOH, wherein n is an integer from 1 to 17.
A method of stabilizing and retarding discoloration of an ointment composition having an oleaginous base and containing about 0.5 to about 1.5% yellow mercuric oxide by weight of the composition, comprising the addition to the composition of about 0.1 to about 10.0% by weight of a stabilizing compound selected from the group consisting of alkanoic acids of formula CH.sub.3 (CH.sub.2).sub.n COOH, wherein n is an integer from 4 to 22 benzoic acid and arylalkanoic acids of formula C.sub.6 H.sub.5 (CH.sub.2).sub.n COOH, wherein n is an integer from 1 to 17.
Dependencies are inferred from the claim text.