Active ingredient dosage device
AssigneeImperial Chemical Industries PLC
InventorsJohn Hoy, Phillipus J. van Rensburg
Life of this patent
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Abstract
A method of making a dosage device comprises admixing at least one active ingredient which is in solid form at 25.degree. C. and which has an average particle size of less than 5 microns, with a disintegrating agent, to provide a compressible mix; and compressing the mix into a unitary dosage device.
Claims9
A dosage device which is in compressed unitary form and which comprises an admixture of a pesticide which is in solid form at 25.degree. C., is sparingly soluble in water, and has an average particle size of 1 to 3 microns, and a disintegrating agent, with the device being capable of disintegrating in water to form a suspension of the pesticide in the water, when introduced into sufficient water such that the concentration of the pesticide in the water is above the solubility limit of the pesticide in water, with the average particle size of the pesticide in the suspension being in the range of 1 to 3 microns.
A dosage device which is in compressed unitary form and which comprises an admixture of a pesticide which is in solid form at 25.degree. C., is sparingly soluble in water, and has an average particle size of less than 5 microns, and a disintegrating agent, with the device being capable of disintegrating in water to form a suspension of the pesticide in the water, when introduced into sufficient water such that the concentration of the pesticide in the water is above the solubility limit of the pesticide in water.
A dosage device comprises:
- 5-60% by mass of a pesticide selected from the group consisting of atrazine, simazine, cyanazine, terbuthylazine, diuron, chlorsulfuron phuron, metsulfuron, tralkoxydim, 2-(2-chloro-4-mesylbenzoyl) cyclohexane-1,3-dione, deltamethrin, lindane, carbaryl, endosulfan, carbofuran, thiophanate methyl, carbendazim, flutriafol, hexaconazole, chlorothalonil, copper oxychloride, captan, thiram, hexythiazox, cyhexatin, amitraz and combinations thereof;
- 3-50% by mass of a disintegrating agent selected from the group of cross-linked polyvinyl pyrrolidone, a modified cellulose gum, a sodium starch glycolate, an acid/base combination and combinations thereof;
- 10-30% by mass of a binder selected from the group consisting of a microfined cellulose, lactose monohydrate and combinations thereof;
- 0.5%-10% by mass of a flow improving agent;
- 0.5-5% by mass of a wetting/dispersing agent selected from the group consisting of sodium lignosulphonate, sodium naphthalene sulphonic acid/formaldehyde condensate, sodium alkyl aryl sulphonate, a nonyl phenol alkylene oxide, a sodium lauryl sulphate, a sodium diisopropyl naphthalene sulfonate, a sodium salt of naphthalene sulfonic acid formaldehyde condensate, oxyethylated polyarylphenol phosphate and combinations thereof;
- 0.5-2% by mass of a lubricant;
- 2-30% by mass of a filler selected from the group consisting of soluble starch, urea, sodium chloride and combinations thereof.
Dependencies are inferred from the claim text.