Prosthesis of foam polyurethane and collagen and uses thereof
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsLeonard A. Trudell, Anthony D. Whittemore
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Abstract
An implantable medical prosthesis is provided having a uniform mixture of foam polyurethane and collagen. The prosthesis can be shaped into an elongated hollow body tube useful for implantation in an animal. Alternatively, the prosthesis can be shaped into biocompatible units useful as soft-tissue replacements or as matrices for sustained-release vehicles.
Claims15
A prosthesis useful for implantation in an animal, wherein said prosthesis comprises:
- at least one layer of a uniform mixture of closed-cell foam polyurethane and collagen in the shape of
- an elongated hollow body tube, said hollow body tube being open at both ends and defining a confined-flow passageway.
A method for implanting a vascular prosthesis which comprises suturing a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen into a blood vessel, tissue or other organ.
A method for implanting a ureteral prosthesis which comprises replacing the ureter, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
A method for implanting a urethral prosthesis which comprises replacing the urethra, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
A method for implanting a biliary prosthesis which comprises replacing the bile duct, or a portion thereof, with a prosthesis having at least one layer containing a uniform mixture of foam polyurethane and collagen.
Dependencies are inferred from the claim text.