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US 5,206,265 AGranted
Iron citrate complex, process for its production, and its pharmaceutical
AssigneeSchering Corporation
InventorsHans-Jorg Vidic, Eraldo Antonini, deceased
Life of this patent
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Abstract
The invention relates to an iron citrate micellar complex having a composition of 10.6% carbon, 2.62% hydrogen, 50.2% oxygen, 32% iron, and 4.6% sodium; a molecular weight of about 33,000 (HPLC-LALLS measurement); and the empirical formula (C.sub.31 H.sub.92 O.sub.110 Fe.sub.20 Na.sub.7).sub.n ; to a process for its production; and to its pharmaceutical use.
Claims5
An iron citrate micellar complex, which is a brown solid having the properties set out below:
- (a) average composition by weight of about:
- 10.6% carbon, 2.62% hydrogen, 50.2% oxygen, 32% iron, 4.6% sodium;
- (b) molecular weight about 33,000 (HPLC-LALLS measurement);
- (c) empirical formula (C.sub.31 H.sub.92 O.sub.110 Fe.sub.20 Na.sub.7).sub.n wherein n=9-10;
- (d) soluble in water, glycerol-water mixtures, practically insoluble in conventional organic solvents;
- (e) ultraviolet absorption in water;
- .lambda.max (470 nm);
- E.sub.1 cm.sup.1% =23-26.5;
- (f) resistance (1% strength solution) 600-750 .OMEGA..cm;
- (g) turbidity pH (1% strength solution) 2.6-2.8.
7 more elements
Dependencies are inferred from the claim text.